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Proteomics and Orthodontic Root Resorption

NCT04291443 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-03-02

No results posted yet for this study

Summary

The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single biological pathway. To our Knowledge, no studies have been employed Gingival crevicular fluid (GCF) proteomic analysis to identify potential biomarkers for OIIRR. Therefore; the aim of this study is to use the advantage of testing a package of biomarkers via doing proteomic analysis of GCF which could help in making a more precise personalize diagnosis and treatments, thereby providing orthodontists additional information that cannot be deduced from clinical parameters.

Conditions

  • Root Resorption
  • Orthodontic Appliance Complication
  • Orthodontic Pathological Resorption of External Root
  • Gingival Diseases
  • Tooth Plaque
  • Tooth Diseases

Interventions

PROCEDURE

Heavy Force (225g)

Orthodontic Force

PROCEDURE

Light Force (25g)

Orthodontic Force

Sponsors & Collaborators

  • University of Baghdad

    lead OTHER

Principal Investigators

  • Harraa S. Mohammed-Salih, MSc. · University of Baghdad

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
32 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2019-07-01
Completion
2019-07-01

Countries

  • Iraq

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04291443 on ClinicalTrials.gov