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Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane

NCT01860495 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2013-05-22

No results posted yet for this study

Summary

One of the most important elements suggested to be provided through membrane perforations to augment regeneration are cell released growth factors from the overlying periosteal and gingival cells. A direct correlation could exist between the number of such cells and their available released growth factors. To test this assumption, this study was designed to evaluate levels of bone morphogenetic protein-2 in gingival crevicular fluid (GCF) during the early stages of healing for sites treated by MPM compared to that of the occlusive barrier membranes.

Conditions

  • Periodontal Pocket

Interventions

PROCEDURE

perforated membrane

perforated membrane that could give a chance for posetive contributionn of periosteal and gingival mesenchymal stem cells in periodontal regeneration

PROCEDURE

G2

tradetional occlusive collagen membrane

Sponsors & Collaborators

  • Al-Azhar University

    lead OTHER

Principal Investigators

  • Ahmed Y Gamal, PhD · Al Azhar universty, faculty of dentistry, cairo, egypt

  • Mohamed M Aziz, BCH · al azhar universty, cairo, egypt

  • Mohamed M Helmy, MSD · al azhar universty

  • Vencint J Iacono, PhD · Stony Brook Uiversty

Eligibility

Min Age
31 Years
Max Age
51 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2012-05-31
Completion
2012-12-31

Countries

  • Egypt

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01860495 on ClinicalTrials.gov