Muscular Biomarkers in Amyotrophic Lateral Sclerosis
NCT02670226 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 37
Last updated 2025-12-22
Summary
The first objective is to find some biomarkers, or a profile of biomarkers of ALS to help to diagnosis. The second objective is to better understand the pathogenesis of this disease by the exploration of muscle, blood and satellite cells metabolomes and transcriptomes.
Conditions
Interventions
- OTHER
-
Samples
Blood samples, muscle biopsy
Sponsors & Collaborators
-
University Hospital, Tours
lead OTHER
Principal Investigators
-
Hélène BLASCO, MD · [email protected]
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-03-29
- Primary Completion
- 2019-10-15
- Completion
- 2019-12-09
Countries
- France
Study Locations
More Related Trials
-
Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
NCT07007390 ·Status: NOT_YET_RECRUITING
-
Study of Predictive Factors of Progression of Motor Neurone Disease
NCT02360891 ·Status: COMPLETED
-
Genomic Translation for Amyotrophic Lateral Sclerosis Care
NCT02795897 ·Status: COMPLETED
-
Identification of Early Markers for ALS
NCT07213440 ·Status: RECRUITING ·Phase: NA
-
Biomarker Development in LGMD2i
NCT04202627 ·Status: COMPLETED
-
Study of miRNA Expression Pattern as Diagnostic and Prognostic Biomarker in Amyotrophic Lateral Sclerosis
NCT01992029 ·Status: TERMINATED
-
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
NCT01495390 ·Status: COMPLETED
-
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
NCT05137665 ·Status: RECRUITING
-
New Therapeutic Strategy in ALS Based on Metabolic Status and Associated Metabolic Pathways.
NCT03984708 ·Status: COMPLETED ·Phase: NA
-
New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis
NCT04691011 ·Status: COMPLETED ·Phase: NA
-
Imaging Biomarkers in ALS
NCT02567136 ·Status: RECRUITING
-
A Pilot Study of Biomarkers for Spinal Muscular Atrophy
NCT00756821 ·Status: COMPLETED
-
Muscle Ultrasound: A New Tool for Measuring Progression in Amyotrophic Lateral Sclerosis (ALS)
NCT00838617 ·Status: COMPLETED
-
Expression Profile Study of Macrophages From Patients Affected by ALS or Other Related Motor Impairments
NCT04816227 ·Status: RECRUITING
-
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
NCT06820008 ·Status: RECRUITING
-
Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis
NCT06083584 ·Status: RECRUITING
-
A Longitudinal Analysis of Biomarkers in Patients With ALS
NCT05309408 ·Status: UNKNOWN
-
Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis
NCT02286011 ·Status: UNKNOWN ·Phase: PHASE1
-
Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
NCT07143656 ·Status: ACTIVE_NOT_RECRUITING
-
Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis
NCT06318598 ·Status: RECRUITING
-
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
NCT02327845 ·Status: ENROLLING_BY_INVITATION
-
Neuromuscular Magnetic Stimulation in ALS Patients
NCT03618966 ·Status: COMPLETED ·Phase: PHASE2
-
Identification of Diagnostic And Prognostic Biomarkers From Amyotrophic Lateral Sclerosis (ALS) Skin and Adipose Samples
NCT01948102 ·Status: COMPLETED
-
Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS
NCT02686268 ·Status: COMPLETED
-
Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
NCT05663008 ·Status: RECRUITING