Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives
NCT04257045 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 46
Last updated 2024-07-12
Summary
This trial collects information about factors that affect communication of genetic test results, decision-making, and access to genetic testing in women with hereditary gynecological cancers. Studying individuals who are positive for a genetic mutation and immediate biological family members (including a parent, full-sibling, or child) may help identify cancer genes and other persons at risk.
Conditions
- Breast Carcinoma
- Deleterious CDH1 Gene Mutation
- Deleterious DICER1 Gene Mutation
- Deleterious SMARCA4 Gene Mutation
- Deleterious STK11 Gene Mutation
- Endometrial Carcinoma
- Fallopian Tube Carcinoma
- Ovarian Carcinoma
- Primary Peritoneal Carcinoma
Interventions
- OTHER
-
Interview
Participate in semi-structure, in-depth qualitative interviews
- OTHER
-
Questionnaire Administration
Complete questionnaires
- OTHER
-
Survey Administration
Complete survey
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Jose A Rauh-Hain · M.D. Anderson Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-08-21
- Primary Completion
- 2024-07-09
- Completion
- 2024-07-09
Countries
- United States
Study Locations
More Related Trials
-
Clinical Outcomes for Offering Genetic Testing in a Tiered Approach
NCT04902144 ·Status: COMPLETED ·Phase: NA
-
Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
NCT04009148 ·Status: ACTIVE_NOT_RECRUITING
-
Racial and Genetic Biomarkers of Response in Tissue Samples From Patients With Endometrial Cancer
NCT01198171 ·Status: COMPLETED
-
Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
NCT07062016 ·Status: RECRUITING
-
Molecular Genetics Studies of Cancer Patients and Their Relatives
NCT04185935 ·Status: RECRUITING
-
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
NCT00579163 ·Status: ACTIVE_NOT_RECRUITING
-
Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients
NCT06875700 ·Status: RECRUITING
-
Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
NCT05694559 ·Status: RECRUITING ·Phase: NA
-
Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression
NCT01433224 ·Status: COMPLETED
-
Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study
NCT06274541 ·Status: COMPLETED
-
Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
NCT01441089 ·Status: RECRUITING
-
Genetic Study of Patients Previously Treated With Flavopiridol on Clinical Trial NCI-97-C-0171C
NCT00040729 ·Status: COMPLETED
-
Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study
NCT05772130 ·Status: RECRUITING ·Phase: NA
-
Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes
NCT06927947 ·Status: RECRUITING ·Phase: NA
-
Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome
NCT04508764 ·Status: TERMINATED ·Phase: NA
-
Reliability and Interest of Circulating Tumor DNA in Endometrial Cancers.
NCT04456972 ·Status: COMPLETED ·Phase: NA
-
Genomic Analysis of Families With a History of Discordant Cancers
NCT04860453 ·Status: RECRUITING
-
Multimedia Aid for Genetic Testing in Gynecologic Oncology
NCT07084168 ·Status: RECRUITING ·Phase: NA
-
Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial
NCT00904514 ·Status: TERMINATED
-
A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration
NCT06564428 ·Status: RECRUITING
-
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
NCT07106359 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Genetic Characteristics of Metastatic Breast Cancer Patients
NCT04258735 ·Status: UNKNOWN ·Phase: NA
-
Germline Mutations in Patients With Head and Neck Cancer and a Family History of Cancer
NCT00482872 ·Status: COMPLETED
-
Molecular Epidemiology of Pediatric Germ Cell Tumors
NCT05564026 ·Status: RECRUITING
-
Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples
NCT01034033 ·Status: RECRUITING