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Manual Therapy on Activation of the Descending Pain Inhibitory System in Patients With Knee Osteoarthritis

NCT04256135 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2020-07-27

No results posted yet for this study

Summary

Introduction: Knee osteoarthritis is a clinical syndrome which is characterized by pain. It has been shown to cause changes in the nervous system leading to central sensitization. There are factors involved in this disease such as sex (female) or obesity. The most recommended therapy is physical therapy, but manual therapy is needed to cause changes in central sensitization.

Methods: Experimental, prospective, parallel and longitudinal double-blind study, in which two groups are performed: group A (AP mobilizations) and group B (Mulligan's mobilizations). Different variables and questionnaires were used: pressure pain threshold, temporal summation, pain modulation, central sensitization inventory, WOMAC, Times Up \& GO, numerical rating scale, Beck, STAI, kinesiophobia, catastrophism, Barthel and mini- cognitive test

Conditions

  • Musculoskeletal Manipulations
  • Osteoarthritis, Knee

Interventions

OTHER

Mulligan mobilization

Mobilization will be performed while the patient actively performs knee flexion and/or extension depending on the patient's painful or limited movements. Three series of ten repetitions will be performed.

OTHER

AP Maitland mobilization

The joint mobilization, will be carried out in the knee with both hands, with displacement of the tibia from the front to the back of the femur in an oscillatory way without pain, will be carried out in blocks of 2 minutes with rests of 30 seconds with a duration of about 6 minutes.

Sponsors & Collaborators

  • Universidad Rey Juan Carlos

    lead OTHER

Principal Investigators

  • Josué Fernández Carnero, Phd · Universidad Rey Juan Carlos

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-04-30
Primary Completion
2020-05-15
Completion
2020-06-10

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04256135 on ClinicalTrials.gov