The Influence of Type of Anesthesia on Postoperative Pain
NCT04239794 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 468
Last updated 2023-12-22
Summary
The investigators designed a multi-center prospective randomized controlled trial to study the influence of the type of anesthesia on postoperative pain after laparoscopic colorectal cancer surgery. Half of the participants will be anesthetized with propofol and remifentanil, while the other half will be anesthetized with sevoflurane and remifentanil during the surgery. The investigators will measure opioid consumption and pain score in the acute postoperative phase.
Conditions
- Colo-rectal Cancer
- Anesthesia
Interventions
- DRUG
-
Propofol
General anesthesia during the laparoscopic colorectal surgery is achieved by using a target-controlled intravenous infusion of propofol.
- DRUG
-
Sevoflurane
General anesthesia during the laparoscopic colorectal surgery is achieved by using an inhalation agent (Sevoflurane).
Sponsors & Collaborators
-
Seoul National University Hospital
lead OTHER
Principal Investigators
-
Jin-Tae Kim, PhD · Seoul National University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-02-20
- Primary Completion
- 2023-12-19
- Completion
- 2024-01-31
Countries
- South Korea
Study Locations
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