Autoimmune Features of Neurodegenerative Disorders
NCT04239079 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2025-08-08
Summary
This study is being conducted to better understand the role of inflammation in Parkinson's disease (PD) and Alzheimer's disease (AD). The investigators plan to recruit 30 PD, 30 AD/Amnestic Mild Cognitive Impairment (aMCI), and 60 age matched healthy controls in this study to study the role of immune response in PD and AD.
The study involves up to two study visits involving brief questionnaires and blood draw of up to 250cc (approximately 17 tablespoons) to be collected. More ways to participate, including 1) smaller amount blood donation (up to 100cc per visit for 1-2 visits); and 2) participation via tele-visit and mobile phlebotomy visits (blood donation up to 50cc, \~5 tubes, by a certified mobile phlebotomist at home/location of choice) now available.
Conditions
- Parkinson Disease
- Alzheimer Disease
- Mild Cognitive Impairment
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Karen Marder, MD, MPH · Columbia University
-
David Sulzer, PhD · Columbia University
-
Julian P Agin-Liebes, MD · Columbia University
Eligibility
- Min Age
- 55 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-05-01
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
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