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Different Limb Lengths in Gastric Bypass Surgery

NCT04219787 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 800

Last updated 2023-11-13

No results posted yet for this study

Summary

Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal Roux-en-Y gastric bypass (LRYGB). There is still lack of knowledge why some patients respond much better than others to an identically performed procedure. Therefore, a number of variations of this operation have been introduced over the past 50 years. Increasing the length of small bowel being bypassed has the potential to improve the effect of the operation but buries the risk of nutrient deficiencies. The metabolic effect of LRYGB occurs, in part, independently of weight loss. The mechanisms underlying metabolic improvement through metabolic surgery are not yet fully understood.

Conditions

Interventions

PROCEDURE

Long BPL LRYGB

LRYGB with an 180 cm BPL and an AL of 80 cm.

PROCEDURE

Short BPL LRYGB

The second group will receive a standard LRYGB with a 80 cm BPL and a 180 cm long AL.

Sponsors & Collaborators

  • Clarunis - Universitäres Bauchzentrum Basel

    lead OTHER

Principal Investigators

  • Marko Kraljevic, MD · Clarunis - Universitäres Bauchzentrum Basel

  • Marco Bueter, MD, Professor · University Hospital Zurch

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-01
Primary Completion
2028-11-30
Completion
2028-11-30

Countries

  • Switzerland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04219787 on ClinicalTrials.gov