Volatile Organic Compounds (VOCs) Profile in Colorectal Cancer Patients and Healthy Controls.
NCT04217083 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2020-01-03
Summary
Volatile organic compounds (VOCs) are low molecular weight (\<1 kDa) compounds which represent the final products of cell metabolism. Their composition can be affected by several factors including diet, hormones, environment and the presence of diseases, in particular, cancer.
Colorectal cancer (CRC) is one of the commonest tumours and is an important cause of cancer-related mortality.
The expression of VOCs in breath that are linked to a patient's disease state could offers a powerful, non-invasive approach to identifying CRC patients.
Conditions
- Colorectal Cancer
- Colon Polyp
Interventions
- DIAGNOSTIC_TEST
-
Breath sampling
The alveolar fraction of Colorectal cancer patients and Healthy controls will be sampled using a breath sampler able to fix the volatile organic compound on absorbable tubes
Sponsors & Collaborators
-
Societa Italiana di Chirurgia ColoRettale
lead NETWORK
Principal Investigators
-
Donato Altomare, Prof · Societa Italiana di Chirurgia ColoRettale
Eligibility
- Min Age
- 18 Years
- Max Age
- 95 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-01-02
- Primary Completion
- 2020-12-25
- Completion
- 2021-01-20
Countries
- Italy
Study Locations
More Related Trials
-
Clinical Significance of Detecting CEA and CK20 mRNA-positive Cells in Colorectal Cancer Patients
NCT03337347 ·Status: COMPLETED ·Phase: NA
-
Hybrid-sensor Breath Analysis for Colorectal Cancer Screening
NCT05173077 ·Status: UNKNOWN
-
Earlier Detection and Optimization of Treatment and Prognosis for Patients With Early-onset Colorectal Cancer
NCT06568679 ·Status: RECRUITING
-
Faecal Immunochemical Test and Urine Volatile Compounds in Adenoma Detection
NCT04146662 ·Status: COMPLETED
-
Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
NCT01239082 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Comparison of Different Fecal Occult Blood Test for Colorectal Cancer Screening
NCT04454099 ·Status: COMPLETED
-
Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
NCT03789162 ·Status: COMPLETED
-
Collection of Blood, Urine, and Stool to Monitor MetastaticColorectal Cancers
NCT03563651 ·Status: COMPLETED
-
"High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)"
NCT04323813 ·Status: UNKNOWN
-
Evaluation of Some Risk Factors Associated With Colorectal Cancer
NCT05170360 ·Status: UNKNOWN
-
Point of Care Test to Diagnosed Colorectal Cancer and Polyps in Low Middle Income Countries
NCT03173729 ·Status: COMPLETED
-
Dissecting the Biology of Early-onset Colorectal Cancer
NCT05916443 ·Status: UNKNOWN
-
Clinical Application of an Automated Liquid Biopsy Platform for Early Detection of Colorectal Cancer
NCT03476122 ·Status: UNKNOWN
-
Validation of Advanced Colorectal Neoplasm Risk Categories in a Prospective Cohort in Mexico
NCT05661292 ·Status: UNKNOWN
-
CARE-CRC: Microbiome Insights and Correlations for Risk and Outcomes in Colorectal Cancer
NCT06734156 ·Status: RECRUITING
-
Early Onset Colorectal Cancer Detection
NCT06342401 ·Status: RECRUITING
-
The Colorectal Breath Analysis (COBRA) Study
NCT03699163 ·Status: COMPLETED
-
Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients
NCT05068531 ·Status: RECRUITING
-
Molecular Pathology of Colorectal Cancer: Investigating the Role of Novel Molecular Profiles, microRNA's, and Their Targets in Colorectal Cancer Progression
NCT03309722 ·Status: UNKNOWN
-
Comparison of Fecal Ribonucleic Acid (RNA) Test With Fecal Occult Blood Test (FOBT) for Detecting Colorectal Cancer and Adenoma
NCT00197405 ·Status: UNKNOWN
-
Colorectal Cancer: Screening vs. Non-Screening
NCT02727894 ·Status: COMPLETED
-
FOcUs on Colorectal CAncer oUtcomes: Long-Term Study
NCT03965325 ·Status: COMPLETED
-
A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method
NCT06100016 ·Status: RECRUITING
-
Prognosis Predicting of CRC Patients Based on Morphology and Molecular Biomaker of CTC
NCT04912882 ·Status: NOT_YET_RECRUITING
-
Reducing Colonoscopies in Patients Without Significant Bowel Disease
NCT04516785 ·Status: COMPLETED