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Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)

NCT04212403 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1350

Last updated 2020-02-24

No results posted yet for this study

Summary

To investigate the use of antibiotic prophylaxis in patients undergoing TURP and TURB. The investigators set up a prospective, randomized controlled trial in which (after exclusion of risk factors) patients will be randomized in receiving levofloxacin (Tavanic) orally or no antibiotics. The exclusion criteria for TURP are a pre-operative transurethral catheter or \> 100 urinary white blood cells in the pre-operative urine sample. The exclusion criteria for TURB are a pre-op catheter or clinical signs of infection.

Conditions

  • Urosepsis
  • Bladder Cancer
  • Prostate Hyperplasia
  • Antibiotic Resistant Strain
  • Antibiotic Resistant Infection
  • Antibiotic-associated Diarrhea
  • Antibiotic Toxicity

Interventions

DRUG

Levofloxacin

The control group receives AMP.

Sponsors & Collaborators

  • Jessa Hospital

    lead OTHER

Principal Investigators

  • Koenraad van Renterghem, PhD · UHasselt

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-17
Primary Completion
2019-12-23
Completion
2019-12-23

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04212403 on ClinicalTrials.gov