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Troponin Excretion in Urine in Patients With and Without Chronic Kidney Disease

NCT04211610 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 131

Last updated 2024-01-17

No results posted yet for this study

Summary

In this study, in order to better understand the mechanism of troponin clearance and the reason for elevated troponin levels in patients with CKD, we aim to evaluate quantitatively the excretion of troponin in the urine in patients with and without CKD, and with and without myocardial injury. We will compare urinary troponin levels with blood troponin levels in these patients. In addition, we will compare the levels of hs-cTnT and hs-cTnI in the patients' sera and urine.

Conditions

  • Chronic Kidney Diseases
  • Acute Myocardial Infarction

Interventions

DIAGNOSTIC_TEST

Blood and urine sampling

* Blood tests - hs-cTnT, hs-cTnI, complete metabolic panel including urea, creatinine, albumin and myoglobin * Urine tests - hs-cTnT, hs-cTnI, urea, creatinine, albumin, total protein, β2-microglobulin.

Sponsors & Collaborators

  • Soroka University Medical Center

    lead OTHER

Principal Investigators

  • Yosef Haviv, MD · Soroka UMC, Nephrology Department, Director

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04211610 on ClinicalTrials.gov