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Effect of RIC on 2,3-BPG in Erythrocyte (RIC-BPG)

NCT04192578 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2020-12-01

No results posted yet for this study

Summary

Under hypoxia or high-altitude hypoxia ,it has been found that 2,3-bisphosphoglycerate(2,3-BPG) in erythrocyte increased and facilitated oxygen release to tissues.Remote Ischemic Conditioning(RIC) can also cause hypoxic conditions in local limbs.Thus,we hypothesize that whether RIC could also increase 2,3-BPG in erythrocyte.

Conditions

  • 2,3-Bisphosphoglycerate

Interventions

DEVICE

remote ischemic conditioning

RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Sponsors & Collaborators

  • Capital Medical University

    lead OTHER

Principal Investigators

  • Xunming Ji, MD, PhD · Xuanwu Hospital, Beijing

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-15
Primary Completion
2021-03-15
Completion
2021-03-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04192578 on ClinicalTrials.gov