Myotonic Dystrophy Type 1 Aerobic Exercise Study
NCT04187482 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13
Last updated 2022-03-14
Summary
Myotonic dystrophy type 1 (DM1) is a genetic disease that primarily targets skeletal muscle resulting in severe weakness and muscle loss. As a result, individuals suffering from DM1 become very inactive and lose mobility resulting in a lower quality of life. This study will investigate the effect of a 12-week moderate intensity exercise protocol on skeletal muscle function and cellular benefits in DM1 patients.
Conditions
- Myotonic Dystrophy 1
- Muscular Dystrophies
Interventions
- OTHER
-
Exercise training
All participants with DM1 will undergo a 12-week aerobic exercise training intervention on a cycle ergometer
Sponsors & Collaborators
- lead OTHER
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-12-06
- Primary Completion
- 2020-03-29
- Completion
- 2021-11-01
Countries
- Canada
Study Locations
More Related Trials
-
The Effects of Trunk Exercises on Upper Extremity and Respiratory Functions in DMD
NCT04669847 ·Status: COMPLETED ·Phase: NA
-
Investigation of the Effects of Functional Inspiratory Muscle Training Applied With Tele-Rehabilitation on Respiratory and Functional Parameters and Quality of Life in Children With Duchenne Muscular Dystrophy: Randomized Controlled Study
NCT07172737 ·Status: COMPLETED ·Phase: NA
-
Safety and Effectiveness of Resistance Exercise Training in Patients With Pompe Disease.
NCT02654886 ·Status: COMPLETED ·Phase: NA
-
Muscle Oxygenation in Effort in Neuromuscular Diseases
NCT02789059 ·Status: COMPLETED ·Phase: NA
-
Personalized Training for People With Rare Neuromuscular Disorders
NCT06708468 ·Status: RECRUITING ·Phase: NA
-
High-intensity Strength Training in Myositis
NCT04486261 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of 5-week Digital Respiratory Practice in Children With Duchenne and Becker Muscular Dystrophies.
NCT06363526 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
NCT03046095 ·Status: COMPLETED ·Phase: NA
-
Physical Training Introduction in Lifestyle of Facioscapulohumeral Dystrophy Patients
NCT01116570 ·Status: COMPLETED ·Phase: NA
-
Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse
NCT06350591 ·Status: COMPLETED ·Phase: NA
-
Inspiratory Muscle Training in Nemaline Myopathy
NCT03728803 ·Status: COMPLETED ·Phase: NA
-
Expiratory Muscle Strength Training (EMST) in Neuromuscular Disorders
NCT04009408 ·Status: UNKNOWN ·Phase: NA
-
Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)
NCT04334343 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Effect of Aerobic Training in Patients With Oculopharyngeal Muscular Dystrophy
NCT02158156 ·Status: UNKNOWN ·Phase: NA
-
Respiratory Muscle Strength in Patients With NMD
NCT01555905 ·Status: TERMINATED ·Phase: NA
-
Natural History of Cardiac and Respiration Function in Patients With Muscular Dystrophies on Home Mechanical Ventilation
NCT02501083 ·Status: UNKNOWN
-
Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
NCT01108575 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Postural Spirometry Changes in Ambulatory Myotonic Dystrophy Patients
NCT01242007 ·Status: COMPLETED ·Phase: NA
-
Respiratory Muscle Function in Heart Failure
NCT03924479 ·Status: COMPLETED ·Phase: NA
-
Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan Syndrome
NCT04553094 ·Status: COMPLETED ·Phase: NA
-
Bicycle Training on Ventilatory Functions in Duchenne Muscular Dystrophy
NCT05849688 ·Status: UNKNOWN ·Phase: NA
-
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473 ·Status: RECRUITING ·Phase: NA
-
Defining 31Phosphorous Magnetic Resonance Spectroscopy Characteristics in Patients With Mitochondrial Myopathy
NCT01301235 ·Status: COMPLETED
-
High Intensity Training in Patients With Facioscapulohumeral Muscular Dystrophy
NCT02159963 ·Status: COMPLETED ·Phase: NA
-
Strength Training Augmenting Rehabilitation
NCT05097092 ·Status: UNKNOWN ·Phase: NA