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Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

NCT04182997 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2025-05-04

No results posted yet for this study

Summary

The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.

Conditions

  • Lumbar Disc Herniation

Interventions

DRUG

Dexamethasone

Patients included in the treatment group will have their surgical site lavaged with dexamethasone at the end of their surgery.

DRUG

saline 0.9%

Patients included in the placebo group will have their surgical site lavaged with sterile saline at the end of their surgery.

Sponsors & Collaborators

  • University of Missouri-Columbia

    lead OTHER

Principal Investigators

  • Don Kim Moore, MD · Missouri Orthopaedic Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-21
Primary Completion
2026-10-31
Completion
2026-10-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04182997 on ClinicalTrials.gov