Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)
NCT04181164 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2021-09-01
Summary
The study aims to evaluate the bone architecture and bone strength in adults with Hypophosphatasia (HPP).
Conditions
- Hypophosphatasia (HPP)
Interventions
- OTHER
-
Microindentation
Microindentation is a new technology directly measuring bone strength by a minimal invasive technique.
- OTHER
-
High resolution peripheral quantitative computed tomography (HRpQCT)
HRpQCT scan can assess the cross-sectional geometry of the bone and is an appropriate investigation to evaluate bone quality.
- BIOLOGICAL
-
Biochemical analysis of different bone markers.
Measurement of different bone markers by biochemical analysis of blood samples.
Sponsors & Collaborators
-
Odense University Hospital
collaborator OTHER -
Hvidovre University Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-10-01
- Primary Completion
- 2021-09-30
- Completion
- 2021-12-30
Countries
- Denmark
Study Locations
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