The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint
NCT04177433 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 61
Last updated 2026-04-02
Summary
This randomized clinical trial (RCT) will evaluate 6-month outcomes following intra-articular injections for arthritis of the thumb carpometacarpal (CMC) joint by comparing corticosteroid plus local anesthetic versus saline (placebo) plus local anesthetic.
Conditions
- Osteoarthritis of the Carpometacarpal Joint
- Thumb Osteoarthritis
Interventions
- DRUG
-
Depo-Medrol Injectable Product
Corticosteroid
- DRUG
-
Saline
Placebo
Sponsors & Collaborators
-
University of Alberta
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-12-02
- Primary Completion
- 2025-09-29
- Completion
- 2025-12-31
Countries
- Canada
Study Locations
More Related Trials
-
Single Blinded First CMC Osteoarthritis Treatment
NCT03196310 ·Status: TERMINATED ·Phase: NA
-
Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
NCT03379168 ·Status: COMPLETED ·Phase: NA
-
An Open Label Trial for Treating Carpometacarpal Osteoarthritis of the Thumb: Pilot Study
NCT00198029 ·Status: COMPLETED ·Phase: NA
-
Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study
NCT02318433 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of LG00034053 in Patients With Knee OA
NCT05237752 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
NCT02102620 ·Status: COMPLETED ·Phase: PHASE4
-
Using Ultrasonography to Predict Clinical Response to Intraarticular Corticosteroids in Knee Osteoarthritis
NCT00414427 ·Status: COMPLETED ·Phase: NA
-
Injection of Autologous Adipose Tissue for Treatment of Osteoarthritis in the Knee
NCT03399630 ·Status: COMPLETED ·Phase: NA
-
Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis
NCT04791202 ·Status: UNKNOWN ·Phase: PHASE3
-
A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee
NCT02024529 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Steroid Injections in a Knee With Osteoarthritis
NCT01230424 ·Status: COMPLETED ·Phase: PHASE4
-
Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee
NCT03485157 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of Five Intraarticular Strategies on Knee Osteoarthritis
NCT03783455 ·Status: COMPLETED ·Phase: NA
-
A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis
NCT02242435 ·Status: COMPLETED ·Phase: PHASE3
-
Gel-200 Extension and Open-Label Study in Osteoarthritis of the Knee
NCT00450112 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Study of CG100649 for Primary Osteoarthritis in Male Subjects
NCT00530452 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis
NCT00171665 ·Status: COMPLETED ·Phase: PHASE3
-
Cell-free Stem Cell-derived Extract Formulation for Knee Osteoarthritis
NCT04971798 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
NCT06359665 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1
-
Study of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the Knee
NCT01887678 ·Status: COMPLETED ·Phase: PHASE3
-
Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis
NCT07171840 ·Status: COMPLETED ·Phase: PHASE3
-
Does Injection Site Matter? A Randomized Controlled Trial to Evaluate Efficacy of Knee Intraarticular Injections on Improval of Patient Reported Outcomes.
NCT02176304 ·Status: COMPLETED ·Phase: PHASE4
-
Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis
NCT02576249 ·Status: COMPLETED ·Phase: PHASE4
-
Intra Articular Injection of Microfat and PRP in Knee Osteoarthritis
NCT04352075 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)
NCT04949087 ·Status: RECRUITING ·Phase: NA