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Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study

NCT04133740 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2019-10-28

No results posted yet for this study

Summary

During surgery high concentrations of supplementary oxygen are routinely administrated. However, there is increasing evidence of potential harm with liberal oxygen therapy. The hypothesis of the present study is that oxygen therapy adjusted to a normal arterial oxygen target is feasible and will attenuate the side effects of supplementary oxygen therapy. The study design is a before-and-after study in which 25 patients will follow the standard regime with high concentrations of oxygen therapy and 25 patients will be treated with oxygen to achieve a normal value of arterial oxygenation.

Conditions

  • Hyperoxia
  • Cardiac Surgery
  • Cardiopulmonary Bypass
  • Acute Lung Injury
  • Oxygen Toxicity

Interventions

DRUG

Oxygen

Liberal versus conservative oxygen therapy.

Sponsors & Collaborators

  • University of Aarhus

    collaborator OTHER

  • Aalborg University Hospital

    lead OTHER

Principal Investigators

  • Bodil S Rasmussen, MD · Aalborg University Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2019-07-15
Completion
2020-07-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04133740 on ClinicalTrials.gov