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Noninvasive VNS to Facilitate Excitability in Motor Cortex

NCT04130646 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2025-04-20

Study results available
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Summary

Transcranial Magnetic Stimulation (TMS) positively influences motor rehabilitation in stroke recovery. Transcutaneous auricular vagus nerve stimulation (taVNS) has shown effects on cortical plasticity. We investigate whether combination of TMS and taVNS is more effective at motor cortex excitability than either modality alone.

Conditions

  • Stroke
  • Stroke Sequelae
  • Motor Activity

Interventions

DEVICE

Transcranial Magnetic Stimulation

transcranial magnetic stimulation delivers magnetic pulses to the brain through the scalp/skull

DEVICE

transcutaneous auricular vagus nerve stimulation (taVNS)

non-invasive vagus nerve stimulation delivers electricity to the ear

Sponsors & Collaborators

  • Medical University of South Carolina

    lead OTHER

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-03-15
Primary Completion
2023-06-12
Completion
2024-12-06
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04130646 on ClinicalTrials.gov