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Analyses of Interleukin-6, Presepsin and Pentraxin-3 in the Diagnosis and Severity of Late-onset Preeclampsia

NCT04126902 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2019-10-15

No results posted yet for this study

Summary

Introduction: The etiology/pathophysiology of preeclampsia remains an enigma. Cellular immunity is a key factor in the etiology of late-onset preeclampsia (L-PrE). Presepsin is split out from the phagocytes membranes after phagocytosis. To investigators knowledge, this is the first study in literature to investigate maternal blood concentrations of presepsin in preeclampsia and healthy pregnant women.

Methods: The investigators examined maternal plasma interleukin-6, presepsin and pentraxin-3 concentrations in pregnant women with (n=44) and without L-PrE (n=44). These three inflammatory markers concentrations measured using enzyme-linked immunosorbent assays were compared.

Conditions

Interventions

OTHER

interleukin-6, presepsin and pentraxin-3

measurements and compare

Sponsors & Collaborators

  • Cengiz Gokcek Women's and Children's Hospital

    lead OTHER

Principal Investigators

  • Ali Ovayolu, MD · Cengiz Gokcek WCH

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-06-06
Primary Completion
2019-01-30
Completion
2019-09-30

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04126902 on ClinicalTrials.gov