Thiol/Disulphide Homeostasis and Preeclampsia
NCT03927014 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2020-06-11
Summary
Objective: To evaluate serum evaluate thiol/ disulfide levels in preeclampsia and address its relationship with its severity.
Methods: This prospective study will include 50 pregnancies complicated with preeclampsia and 50 healthy pregnancies. The blood for analysis will obtain at the admission and serum thiol/ disulfide levels will measure using commercially available reagent kits. The continuous values were evaluated using Student's t-test, and categorical values were evaluated using the Chi-square test. P values \< .05 were accepted as significant.
Conditions
Interventions
- OTHER
-
thiol/disulfide levels
Venous blood will sample from the antecubital veins for measuring the serum concentration of thiol/disulfide levels. The serum thiol/disulfide levels will measure using commercially available reagent kits, which is produced to detect human thiol/disulfide levels (Rel Assay Diagnostics Gaziantep, Turkey). The thiol/disulfide levels measurements were performed in accordance with the company's protocol.
Sponsors & Collaborators
-
Cengiz Gokcek Women's and Children's Hospital
lead OTHER
Principal Investigators
-
Ali Ovayolu, MD · Cengiz Gokcek WCH
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-04-25
- Primary Completion
- 2020-01-01
- Completion
- 2020-02-05
Countries
- Turkey (Türkiye)
Study Locations
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