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Dietary Nitrate and Erectile Dysfunction

NCT04116060 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2021-01-25

No results posted yet for this study

Summary

An expanding number of studies suggest a therapeutic role for nitrate and nitrite, most notably in treatment and prevention of cardiovascular disease including ischemia-reperfusion injury and hypertension. The nutritional aspects of these cardioprotective effects are particularly intriguing since nitrate is abundant in our everyday diet. Nitrate improves vascular functions in old adults and improves ischemia reperfusion injury in experimental models.

Whether dietary nitrate improves erectile dysfunction is not known and will be investigated in the present study.

Conditions

Interventions

DIETARY_SUPPLEMENT

Dietary Nitrate

Oral dietary nitrate supplementation with (0,12 mmol/kgBW sodium-nitrate)

DIETARY_SUPPLEMENT

Control

Placebo Comparator: Dietary sodium-chloride dissolved in water (0,12 mmol sodium-chloride/kgBW/day)

Sponsors & Collaborators

  • University Hospital, Essen

    lead OTHER

Principal Investigators

  • Tienush Rassaf, Prof · University Hospital, Essen

  • Christos Rammos, MD · University Hospital, Essen

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
80 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-17
Primary Completion
2021-06-01
Completion
2021-08-01

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04116060 on ClinicalTrials.gov