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Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis

NCT04103242 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23

Last updated 2024-12-04

No results posted yet for this study

Summary

Infertile women undergoing hysteroscopy for diagnostic or therapeutic indication are asked to donate a sample of endometrium.

Endometrial samples of study participants are examined for signs of chronic endometritis by immunohistochemical analysis.

High-throughput sequencing of the microbial 16s ribosomal ribonucleic acid (rRNA) subunit is performed to identify and quantify the microbes present in the sample.

Obstetric and reproductive outcome is recorded 12 months after hysteroscopy (telephone interview).

Conditions

  • Non Specific Chronic Endometritis
  • Infertility, Female

Interventions

OTHER

16s rRNA gene sequencing

High-throughput sequencing of the microbial 16s rRNA subunit to define the abundance of microbial phyla and genera

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Rebecca Moffat, MD · University Hospital, Basel, Switzerland

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-02
Primary Completion
2020-02-12
Completion
2021-02-28

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04103242 on ClinicalTrials.gov