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Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis

NCT05205993 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2023-02-24

No results posted yet for this study

Summary

Chronic Endometritis (CE) is related to infertility and entails a challenging management. This study investigates the treatment of off-label intrauterine antibiotic infusion either separately or combined with oral antibiotic administration, and it assesses respective performance against the gold standard treatment of oral antibiotic adminstration. Data sourced herein reports on treatment efficiency, defined as a negative diagnosis for chronic endometritis.

Conditions

  • Chronic Endometritis

Interventions

DRUG

Intrauterine infusion

A total of 10 intrauterine infusions of 3ml of ciprofloxacin at a concentration of 200 mg/100 ml

DRUG

Oral administration

per os antibiotic administration as the standard line of strategy for treating CE of doxycycline at a dosage of 100mg twice a day and metronidazole of 500mg twice a day for a total of 30 days

Sponsors & Collaborators

  • National and Kapodistrian University of Athens

    collaborator OTHER

  • Genesis Athens Clinic

    lead OTHER

Principal Investigators

  • Konstantinos Sfakianoudis, MD · Genesis Athens Clinic

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-19
Primary Completion
2024-01-30
Completion
2024-04-30

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05205993 on ClinicalTrials.gov