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Connective Tissue Diseases and Lung Manifestations

NCT04095351 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2020-05-27

No results posted yet for this study

Summary

Despite a number of prospective studies already initiated in the past years, the current epidemiology and course of interstitial lung disease (ILD) and pulmonary hypertension (PH) in patients with connective tissue disease (CTD) is still not well defined, particularly regarding its prevalence, incidence and the management of a broad spectrum of disease presentations.

Major challenges include the identification of patients with progressive disease, the appropriate time point of therapeutic intervention and the underlying driver of disease (inflammatory or pro-fibrotic stimulus or both?).

To address these issues in Western Austria, a progressive registry of patients with CTD exploring routine clinical and pathophysiological characteristics of ILD and PH will be conducted. This multidisciplinary, prospective and observational registry aims to collect comprehensive clinical data on incidence, prevalence and course of disease regarding all PH and ILD presentations in a real-world setting.

Conditions

Interventions

DIAGNOSTIC_TEST

Pulmonary function test

Spirometry or plethysmography, measurement of diffusion capacity

DIAGNOSTIC_TEST

Imaging

Thoracic ultrasound, HRCT as scheduled within routine clinical examinations, echocardiography

BIOLOGICAL

Blood sampling

Standard laboratory test for CTDs as part of routine clinical examination

Sponsors & Collaborators

Principal Investigators

  • Judith Löffler-Ragg, Prof. MD · Medical University Innsbruck, Department Internal Medicine

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-09
Primary Completion
2021-03-01
Completion
2034-10-01

Countries

  • Austria

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04095351 on ClinicalTrials.gov