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Biomarkers in Early-stage Spondyloarthritis

NCT04095169 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 216

Last updated 2020-10-05

No results posted yet for this study

Summary

Axial spondyloarthritis (axSpA) is a group of inflammatory rheumatic conditions with inflammatory back pain caused by inflammation in the sacroiliac joints (SIJ) and back as hallmark.

Currently, no laboratory test or biomarker is cable of differentiating between patients with early-stage axSpA and persisting low back pain of other causes.

The objective of this study is to investigate the predictive value of baseline levels of the biomarkers Complement C3d and high-sensitive C-reactive protein (HsCRP) identifying bone marrow oedema (BME) at MRI of the SIJ at baseline.

Conditions

Interventions

DIAGNOSTIC_TEST

Complement C3d test (blood sample)

Evaluation of C3d levels in EDTA samples from participants

Sponsors & Collaborators

  • Spine Centre of Southern Denmark

    lead OTHER

Principal Investigators

  • Allan Nygaard, MD · Spinecentre of Southern Denmark

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2020-10-01
Completion
2020-10-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04095169 on ClinicalTrials.gov