Ankylosing spondylitis is a chronic inflammatory disease that primarily affects the spine and sacroiliac joints, causing pain and stiffness. Over time it can lead to fusion of the vertebrae and reduced spinal mobility.
Eli Lilly, AbbVie, Vertex, Gilead Sciences and Pfizer were identified as pharmaceutical stocks to watch, with Abbott Laboratories and McKesson appearing on a separate seven-stock list.
The FDA has eased biosimilar approval procedures as these therapies have generated $56 billion in savings since 2015. New guidance eliminates comparative efficacy studies, potentially saving manufacturers $100 million per product and cutting development time by 50%. Despite growth to 23% of the biologics market, a "biosimilar void" threatens $232 billion in missed savings over the next decade.
Bio-Thera Solutions expands its partnership with Intas Pharmaceuticals for BAT2506, a golimumab biosimilar, through an exclusive commercialization agreement for India. The India biosimilars market is projected to grow from $184 million to $1.02 billion by 2035, driven by patent expirations and strategic partnerships.
The European Commission has approved Gotenfia (golimumab), a biosimilar to Simponi developed by Bio-Thera and marketed by STADA, for chronic inflammatory autoimmune diseases across the EU and EEA.
The European Commission has granted marketing authorization for Gotenfia, a golimumab biosimilar to Simponi, developed by Bio-Thera and to be commercialized by STADA across the EU, EEA, UK, Switzerland and selected other countries.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07580092 |
Construct Validity and Responsiveness of EQ-5D-3L and EQ-5D-5L in Patients With Inflammatory Joint Disease |
COMPLETED | |
| NCT07578220 |
Clinical Trial Study on the Improved New Method of Acupotomy for AS |
RECRUITING | NA |
| NCT07534644 |
A Phase I/Ⅱ Clinical Trial for Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Ankylosing Spondylitis |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07510789 |
Impact of Low Back Pain Phenotypes on Function and Quality of Life in Ankylosing Spondylitis |
RECRUITING | |
| NCT07453628 |
Association of Erectile Dysfunction With Neuropathic Pain, Disease Activity, and Functional Status in Male Patients With Axial Spondyloarthritis: A Cross-Sectional Observational Study |
COMPLETED | |
| NCT07396194 |
Ankylosing Spondylitis |
NOT_YET_RECRUITING | |
| NCT07390929 |
Clinical Trial Study on the Improved New Method of Acupotomy for AS |
WITHDRAWN | NA |
| NCT07383805 |
Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis |
NOT_YET_RECRUITING | |
| NCT07348939 |
Effect Of Kinesiology Tape On Pain, Posture, Balance And Respiration In Ankylosing Spondylitis |
COMPLETED | NA |
| NCT07329556 |
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases |
NOT_YET_RECRUITING |
