MedTrace Logo

Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients

NCT04089813 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2019-09-13

No results posted yet for this study

Summary

Metformin has been found to have more and more functions as a commonly used hypoglycemic drug in clinic. It has been found that metformin has anti-inflammatory, anti-tumor and lipid metabolism regulating effects. Basic studies have shown that metformin as an adjuvant drug combined with gabapentin and tramadol is safe and effective in patients with neuropathic pain. Postoperative chronic pain as a common complication has seriously affected the quality of life and mood of patients after surgery.Some studies have shown that chronic pain after partial operation manifests as neuropathic pain. The effect of metformin on chronic pain after thoracic surgery in patients with diabetes mellitus was observed in this experiment, which was compared with patients taking insulin to control blood sugar.

Conditions

  • Postoperative Chronic Pain

Interventions

DRUG

Metformin

Patients use metformin to control blood sugar

Sponsors & Collaborators

  • Xuzhou Medical University

    lead OTHER

Principal Investigators

  • JinDong Liu, M.S · Afliated Hospital of Xuzhou Medical University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-10
Primary Completion
2019-12-09
Completion
2020-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04089813 on ClinicalTrials.gov