Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women
NCT04066283 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 29
Last updated 2024-09-19
Summary
This study will examine markers of vascular endothelial function (vascular health) and metabolic profiles in younger versus older transgender women (people who were assigned male at birth but whose gender identity is female). Data will also be compared to those from cisgender women and men.
Conditions
- Transgender
- Gender Identity
- Vascular Stiffness
- Vascular Inflammation
- Insulin Sensitivity
- Blood Pressure
- Lipid Disorder
- Appetitive Behavior
Interventions
- OTHER
-
No intervention
There was no intervention in this study
Sponsors & Collaborators
-
National Center for Advancing Translational Sciences (NCATS)
collaborator NIH -
University of Colorado, Denver
lead OTHER
Principal Investigators
-
Sean Iwamoto, MD · University of Colorado, Denver
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-04-17
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- United States
Study Locations
More Related Trials
-
Influences of Long Term Hormone Therapy on Physical Fitness and Vascular Function in Transgender Women
NCT06116201 ·Status: COMPLETED ·Phase: NA
-
Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People
NCT06083766 ·Status: RECRUITING
-
Extracellular Vesicles and Endothelial Function in Transgender Subjects
NCT04971447 ·Status: UNKNOWN ·Phase: NA
-
Pain Outcomes Associated With Exogenous Hormone Therapy in Adults
NCT06939257 ·Status: RECRUITING
-
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
NCT04551144 ·Status: TERMINATED
-
Transgender Estradiol Affirming Therapy
NCT05010707 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Estrogen Treatment on Drug Metabolism and Transport
NCT05469204 ·Status: COMPLETED ·Phase: PHASE4
-
Progesterone in Gender Affirming Hormone Therapy Study
NCT06807580 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
NCT04283656 ·Status: COMPLETED ·Phase: PHASE1
-
Gender-Affirming Hormone Therapy and Its Impact on Myocardial Mass and Cardiac Function, Heart, Liver and Pancreatic Fat Content
NCT06291675 ·Status: RECRUITING
-
Prevention of Obesity in Women Via Estradiol Regulation
NCT00687739 ·Status: COMPLETED ·Phase: PHASE3
-
Reduction of Triglycerides in Women on Hormone Replacement Therapy
NCT00023543 ·Status: COMPLETED ·Phase: PHASE2
-
Feminizing Treatment in Transgender Women and Non-binary Persons
NCT05169762 ·Status: RECRUITING
-
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
NCT07187947 ·Status: RECRUITING
-
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
NCT00608062 ·Status: COMPLETED ·Phase: NA
-
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
NCT00001752 ·Status: COMPLETED ·Phase: PHASE2
-
i2TransHealth: Interdisciplinary, Internet-based Trans Health Care
NCT04290286 ·Status: COMPLETED ·Phase: NA
-
Menopause Effects on Vascular Function
NCT03236545 ·Status: COMPLETED ·Phase: NA
-
Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy
NCT06969326 ·Status: RECRUITING ·Phase: PHASE3
-
Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering from Gender Dysphoria
NCT06351501 ·Status: RECRUITING ·Phase: PHASE3
-
Decrease of Libido of Post-Operative Male-Female Transsexuals and a Healthy Female Control Group
NCT00135148 ·Status: COMPLETED
-
Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.
NCT04336891 ·Status: COMPLETED
-
Postprandial Lipidemia After a Meal With Different Types of Fat, Estrogen Treatment, Age and Gender in Healthy Subjects
NCT02383823 ·Status: WITHDRAWN ·Phase: NA
-
Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function
NCT03112226 ·Status: COMPLETED ·Phase: NA
-
Estradiol-Receptor Blockade in Older Men and Women
NCT02271282 ·Status: COMPLETED ·Phase: PHASE1