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AMI Construction in Lower Extremity Residual Limbs

NCT04063592 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2025-10-17

No results posted yet for this study

Summary

This study will involve the development of a novel approach to lower extremity residual limb surgical revision that offers the promise of augmenting volitional motor control, restore proprioception and reverse atrophy

Conditions

  • Amputation

Interventions

PROCEDURE

Residual limb revision

Surgical procedure involving construction of agonist-antagonist myoneural interfaces (AMIs)

Sponsors & Collaborators

  • Massachusetts Institute of Technology

    collaborator OTHER

  • Walter Reed National Military Medical Center

    collaborator FED

  • United States Department of Defense

    collaborator FED

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Matthew J Carty, MD · Brigham and Women's Hospital

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-24
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04063592 on ClinicalTrials.gov