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Motion and IntraCoronary Ecg Ischemia Development Study (MICE)

NCT04061525 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-08-19

No results posted yet for this study

Summary

The concept of the "ischemic cascade" is generally accepted hypothesis, according to which whenever ischemia of the myocardium occurs there is a consequence of events, that always occur in a given order - diastolic dysfunction first, followed by systolic dysfunction, then changes on electrocardiogram (ECG) and finally chest pain sensation. The occurrence of every next stage of cascade means more severe ischemia and respectively - more severe myocardial damage. We propose that mechanical and electrical changes in the myocardium during ischemia appear simultaneously.

Conditions

  • Ischaemic Heart Disease

Interventions

PROCEDURE

Percutaneous coronary intervention with FFR measurement and intracoronary ECG registration

Measurement of fractional flow reserve (FFR), registration of intracoronary ECG and radioscopic registration of wire tip movement in the main and in the side branch in the beginning, at the end and during every step of coronary bifurcation percutaneous intervention.

Sponsors & Collaborators

  • University National Heart Hospital

    lead OTHER

Principal Investigators

  • Dobrin Vassilev · Principal Investigator

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2022-01-31
Completion
2024-01-31

Countries

  • Bulgaria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04061525 on ClinicalTrials.gov