The Effect of Physical Fatigue on Different Balance Tests and Brain Activity in a Healthy Population

Summary

The main objective of this project is:

1\. To assess the influence of physical fatigue on brain functioning during a balance and reaction time task in a healthy population. In a later stage, these experiments could be carried out in a clinical context (e.g. in an ankle sprain population).

The researchers will use a randomized, placebo controlled, counter-balanced, cross-over design. Twenty healthy subjects will visit the lab 3 times. On the first visit (familiarisation trial), the investigators will collect the participants' characteristics. The participants will also be familiarized to the procedures and materials of the experiment during this first visit. The second and third visit contain the experimental setup and will proceed as follows: first, the participants will fill in a pre-test checklist, a mental fatigue scale (M-VAS) and motivation scale. In the mean time a little blood will be collected from the ear lobe to determine lactate and glucose levels; also, blood pressure will be checked.

Next, the subjects will carry out a Y-balance test and a balance reaction-time test. Session rate of perceived exertion (SRPE) is measured to indicate how fatigued the participants feel due to the test battery; also, M-VAS is collected once more, as well blood lactate, glucose and blood pressure. These measures are followed by either a physical fatigue inducing task (Modified 30 seconds Wingate protocol) or time-matched control task (sitting on the bike without pedalling). Afterwards, researchers will collect blood lactate, glucose and blood pressure two times more; participants have to fill in M-VAS (2x), perform the same Y-balance test and balance reaction time test, and fill in the SRPE scale one more time. Heart frequency and EEG will be measured continuously during the trials.

Conditions

• Physical Fatigue
• Return to Sport
• Injury Prevention
• EEG
• Brain Activity
• Balance

Interventions

BEHAVIORAL

Physical Fatigue

Maximal cycling effort for 30s (Wingate modified)

BEHAVIORAL

Control

time-matched task (sitting on the bike without pedalling)

Sponsors & Collaborators

• Vrije Universiteit Brussel

  lead OTHER

Principal Investigators

• Romain Meeusen, Professor · Vrije Universiteit Brussel

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

35 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-07-19

Primary Completion

2020-03-09

Completion

2020-03-09

Countries

• Belgium

Study Locations