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Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis

NCT04024033 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-05-10

No results posted yet for this study

Summary

The medicinal properties of pinecones have been used for years to treat a variety of illnesses. In the mouse model, an extract of pine cones, poly-phenylpropanoid-polysaccharide complex (PPC), has been shown to reduce total serum IgE levels as well as decreased production of IL-4, a cytokine associated with allergic disease. In this study, the investigators aim to determine the effects that PPC will have on total serum IgE levels in adult subjects with perennial rhinitis.

Conditions

  • Perennial Allergic Rhinitis

Interventions

DIETARY_SUPPLEMENT

pine cone extract

pine cone extract capsule

OTHER

placebo

placebo capsule

Sponsors & Collaborators

  • University of South Florida

    lead OTHER

Principal Investigators

  • Dennis Ledford, M.D. · Division of Allergy and Immunology, USF

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2023-10-31
Completion
2023-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04024033 on ClinicalTrials.gov