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Effect of Nasaleze on Nasal Challenge With Allergen

NCT01723397 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2017-01-02

Study results available
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Summary

The objectives of this protocol are:

1. to confirm the inhibitory effect of Nasaleze on the immediate response to nasal challenge with antigen, and
2. to show that inhibition of the immediate response to nasal challenge with antigen by Nasaleze inhibits subsequent inflammatory events.

Conditions

  • Allergic Rhinitis

Interventions

DRUG

Nasaleze Spray

Subjects are treated with over the counter Nasaleze cellulose powder nasal spray then challenged with allergen

OTHER

Placebo spray

Subjects are treated with placebo nasal spray then challenged with allergen

BIOLOGICAL

Allergen

Subjects are challenged with grass or ragweed allergen after treatment with Nasaleze or placebo

Sponsors & Collaborators

  • University of Chicago

    lead OTHER

Principal Investigators

  • Robert M Naclerio, MD · University of Chicago

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-11-30
Primary Completion
2014-07-31
Completion
2014-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01723397 on ClinicalTrials.gov