Sulforaphane Supplementation in Atopic Asthmatics
NCT01845493 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2016-03-09
Summary
The investigators will perform a pilot study of daily treatment with oral sulforaphane (SFN) for 3 days to determine if Nuclear factor (erythroid-derived 2)-like 2 (NRF2) induction is possible with this supplementation regimen in individuals with allergic asthma.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Alpha Sprout Homogenate
Alpha Sprout Homogenate
- DIETARY_SUPPLEMENT
-
Sulforaphane Homogenate
Active
Sponsors & Collaborators
-
University of North Carolina, Chapel Hill
lead OTHER
Principal Investigators
-
Michelle L Hernandez, MD · center for environmental medicine asthma and lung biology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-04-30
- Primary Completion
- 2014-10-31
- Completion
- 2014-10-31
Countries
- United States
Study Locations
More Related Trials
-
Effects of Intranasal Corticosteroid and Montelukast On Nasal Allergen Challenges*
NCT01240889 ·Status: COMPLETED ·Phase: NA
-
Broccoli Sprout Extract Effects on Allergic Inflammation in the Nose
NCT00882115 ·Status: COMPLETED ·Phase: NA
-
Efficacy Study of Sublingual Immunotherapy to Treat Ragweed Allergies
NCT00599872 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 2 Study in Adults Sensitized to Short Ragweed
NCT00670384 ·Status: WITHDRAWN ·Phase: PHASE2
-
Airway Inflammation in Children With Allergic Rhinitis and Intervention
NCT02352168 ·Status: COMPLETED ·Phase: NA
-
Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
NCT04161547 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Bepotastine Besilate Nasal Spray in the Treatment of Seasonal Allergic Rhinitis
NCT01277341 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug
NCT00318747 ·Status: TERMINATED ·Phase: PHASE2
-
An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo
NCT01439815 ·Status: COMPLETED ·Phase: PHASE4
-
Innate Neutrophilic Nasal Inflammation in a Pollen Exposure Chamber
NCT03496103 ·Status: COMPLETED ·Phase: PHASE1
-
Biological Standardization of Allergen Extracts of Pollens of Betula Pendula, Phleum Pratense and Mite Extract of Dermatophagoides Pteronyssinus
NCT01147159 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of Olopatadine Nasal Spray
NCT00578331 ·Status: COMPLETED ·Phase: PHASE3
-
Trial of STAHIST in Seasonal Allergic Rhinitis
NCT01293201 ·Status: COMPLETED ·Phase: PHASE3
-
Topical Allstate and Nasal Allergen Challenge
NCT01231724 ·Status: WITHDRAWN ·Phase: PHASE3
-
Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children
NCT00841256 ·Status: COMPLETED ·Phase: PHASE3
-
Theophylline in Rhinitis
NCT01132781 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety From a High-dosed Sublingual Grass Pollen Preparation
NCT00623701 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Preventive Effects and Mechanisms of Yeast β-Glucan on Upper Respiratory Tract Infections
NCT07085858 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of House Dust Mite Allergen Challenge in Persons Using 1200 mg Gamma Tocopherol Supplements
NCT00466596 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Ragweed (Ambrosia Artemisiifolia) Allergy Immunotherapy Tablet in Adults With Ragweed Allergies (P05751)
NCT01469182 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis
NCT04024033 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Nasal Inflammatory Biomarkers
NCT03450031 ·Status: COMPLETED ·Phase: NA
-
The Effects of Using Yupingfeng Powder with Variation for the Treatment of Allergic Rhinitis
NCT04976023 ·Status: COMPLETED ·Phase: PHASE2
-
The Efficacy and Safety of Sanfujiu on Patients With Persistent Allergic Rhinitis: Randomized Controlled Study
NCT02192645 ·Status: UNKNOWN ·Phase: PHASE3
-
Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract
NCT00927329 ·Status: WITHDRAWN ·Phase: PHASE1