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Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery

NCT04013347 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 167

Last updated 2019-07-09

No results posted yet for this study

Summary

Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal, but shorter or longer intervals have been associated with better oncological outcomes. Moreover, there is a lack of data about clinical postoperative outcomes and different time intervals after the end of NRCT. Here, effect that different time intervals have on postoperative complications with particular regard to the anastomotic dehiscence have been evaluated.

Methods One hundred-sixty-seven patients underwent surgery after long-course NRCT. Three different time intervals were considered: (0-42; 43-56; \>57 days).

Conditions

  • Neoadjuvant Chemoradiotherapy
  • Rectal Tumor
  • Surgery
  • Surgery--Complications

Interventions

PROCEDURE

Rectal Resection

Low Anterior Resection and Abdominoperineal Resection

Sponsors & Collaborators

  • Campus Bio-Medico University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-01-01
Primary Completion
2015-03-01
Completion
2017-03-21

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04013347 on ClinicalTrials.gov