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Appropriate Timing of Surgery After Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

NCT03287843 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 350

Last updated 2022-03-31

Study results available
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Summary

This study aimed to compare the outcomes of early versus late surgical resection in patients who underwent curative total mesorectal excision after neoadjuvant chemoradiation. Half of the participants will undergo surgery before 8 weeks, while the other half will undergo surgery after 8 weeks.

Conditions

  • Neoplasm, Rectum

Interventions

PROCEDURE

Total mesorectal excision before 56 days (4-8 weeks)

Low anterior resection or abdominoperineal resection

PROCEDURE

Total mesorectal excision after 56 days (8-12 weeks)

Low anterior resection or abdominoperineal resection

Sponsors & Collaborators

  • Ege University

    lead OTHER

Principal Investigators

  • Z.Erhan Akgun, Proffesor · Ege University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-01
Primary Completion
2017-01-01
Completion
2022-01-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03287843 on ClinicalTrials.gov