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Study of the Effects of Bronchoalveolar Lavage Liquid in the ARDS on the Functioning of the Neutrophil Polynuclear System

NCT04008225 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2019-07-08

No results posted yet for this study

Summary

Firstly, the study assesses the effect of bronchoalveolar lavage fluid (BAL) from patients in (acute respiratory distress syndrome (ARDS) on the life span of PNNs and on the phagocytosis of apoptotic cells by macrophages and polynuclear neutrophil (PNN).

Then, the effect of an antibody directed against "high-mobility group box 1" protein (HMGB1) and the effect of metformin on efferocytosis are studied.

Conditions

  • ARDS, Human

Interventions

PROCEDURE

Bronchoalveolar lavage

Sponsors & Collaborators

  • Rennes University Hospital

    lead OTHER

Principal Investigators

  • Jean-Marc TADIE, MD, PhD · University Hospital of Rennes

Eligibility

Sex
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-05-05
Primary Completion
2016-05-05
Completion
2016-05-05

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04008225 on ClinicalTrials.gov