Understanding the Role of Genes and Biomarkers in the Inflammation and Blood Clotting Process in Children With Acute Lung Injury
NCT00605527 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 396
Last updated 2020-07-20
Summary
Acute lung injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) is a severe lung condition that causes respiratory failure. This study will examine if differences in genes and biomarkers involved in the inflammation and blood clotting process may affect the severity of and recovery from ALI/ARDS in children hospitalized with the condition.
Conditions
- Respiratory Distress Syndrome, Adult
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of California, San Francisco
lead OTHER
Principal Investigators
-
Anil Sapru, MD, MAS · University of California, San Francisco
Eligibility
- Min Age
- 30 Days
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-11-30
- Primary Completion
- 2016-12-31
- Completion
- 2016-12-31
Countries
- United States
Study Locations
More Related Trials
-
Clinical Features, Treatments, and Outcomes in Acute Respiratory Distress Syndrome (ARDS-CTO)
NCT07186140 ·Status: NOT_YET_RECRUITING
-
The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury
NCT03766204 ·Status: UNKNOWN
-
Discovery of New Early Detection Biomarkers From Peripheral Blood of Acute Respiratory Distress Syndrome(ARDS)
NCT02967471 ·Status: UNKNOWN
-
The Role of Circulating Soluble CD74 in Acute Lung Injury
NCT02201446 ·Status: COMPLETED
-
Indicators of Inflammation and Coagulation in Sepsis
NCT01128283 ·Status: COMPLETED
-
Early Biological and Mechanical Profiling in Sepsis-Associated ARDS
NCT07281911 ·Status: NOT_YET_RECRUITING
-
Serial Changes of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Levels in Patients With Acute Respiratory Distress Syndrome
NCT00557414 ·Status: COMPLETED
-
Biomarkers to Predict Acute Respiratory Distress Syndrome(ARDS) in Patients With Sepsis
NCT05914428 ·Status: UNKNOWN
-
Pulmonary Microbiota and ARDS Mortality
NCT04133558 ·Status: UNKNOWN
-
Validation and Precision Treatment of Inflammatory Subphenotypes in Acute Respiratory Distress Syndrome: A Multicenter Cohort Study
NCT07289711 ·Status: RECRUITING
-
Study on the Correlation Between Alveolar Macrophage-derived Autophagosomes and the Severity of Lung Injury in ARDS
NCT05101694 ·Status: UNKNOWN
-
Study of the Effects of Bronchoalveolar Lavage Liquid in the ARDS on the Functioning of the Neutrophil Polynuclear System
NCT04008225 ·Status: COMPLETED
-
Study of Biomarkers in Patients of Sepsis Complicated With Acute Respiratory Distress Syndrome (ARDS)
NCT04552821 ·Status: UNKNOWN
-
The Mechanism of Extracellular Vesicles Containing Mitochondrial DNA in ARDS Lung Injury Caused by Extrapulmonary Sepsis
NCT05061212 ·Status: UNKNOWN
-
Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome
NCT02265198 ·Status: COMPLETED
-
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain)
NCT02003326 ·Status: TERMINATED ·Phase: NA
-
Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials
NCT00719446 ·Status: COMPLETED
-
The Role and Mechanism of O-GlcNAc Glycosylation Modified HAS2 in the Hyaluronic Acid Synthesis in ARDS
NCT05055557 ·Status: UNKNOWN
-
Biomarker of Lung Injury in ARDS Patients Receiving ECMO Support
NCT01967602 ·Status: UNKNOWN
-
Neutrophil Elastase and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome
NCT02944279 ·Status: COMPLETED
-
Discovery of New Early Detection Biomarkers of Acute Respiratory Distress Syndrome
NCT02625064 ·Status: UNKNOWN
-
Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis
NCT01012115 ·Status: COMPLETED
-
The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis of ARDS ( Acute Respiratory Distress Syndrome )
NCT06825754 ·Status: COMPLETED
-
Feasibility Study of MicroKine Dx System in Critically-ill Pediatric Patients.
NCT04295278 ·Status: UNKNOWN
-
Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients
NCT02070536 ·Status: COMPLETED