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TIPTOP Sulfadoxine-pyrimethamine (SP) Drug Resistance Study

NCT03998839 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 7200

Last updated 2023-06-15

No results posted yet for this study

Summary

The main objective of this study is to monitor SP resistance via molecular markers in the context of the TIPTOP project implementation of community distributed SP for women during pregnancy.

The specific objective is to detect trends over time in the proportion of symptomatic children with a positive rapid diagnostic test (RDT) residing in the areas where C-IPTp is implemented who carry parasites with dhfr/dhps mutations compared to those in control areas with no community SP distribution.

Conditions

  • Malaria in Pregnancy

Interventions

OTHER

Community distribution of Sulfadoxine-pyrimethamine (SP)

Community health workers will distribute SP to pregnant women, targeting at least three times during pregnancy.

Sponsors & Collaborators

  • Barcelona Institute for Global Health

    collaborator OTHER

  • Jhpiego

    lead OTHER

Principal Investigators

  • Elaine Roman, MA · Jhpiego

Eligibility

Min Age
0 Years
Max Age
5 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-05
Primary Completion
2021-11-30
Completion
2021-11-30
FDA Drug
Yes

Countries

  • Democratic Republic of the Congo
  • Madagascar
  • Mozambique
  • Nigeria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03998839 on ClinicalTrials.gov