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Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi

NCT00126906 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 700

Last updated 2005-08-23

No results posted yet for this study

Summary

In Malawi, the standard of care to prevent malaria during pregnancy at the time of the study was a two dose sulfadoxine-pyrimethamine intermittent protective treatment (SP IPT) regimen administered in the second and third trimester of pregnancy. In this investigation, this two dose strategy was compared to a monthly SP regimen. The objective for the study was to determine the efficacy of the different regimens for HIV positive and HIV negative women in the prevention of placental malaria.

Conditions

  • Malaria, Falciparum
  • HIV Infections

Interventions

DRUG

Monthly sulfadoxine/pyrimethamine

DRUG

2-dose sulfadoxine/pyrimethamine

Sponsors & Collaborators

Principal Investigators

  • Scott J Filler, MD, DTM&H · Centers for Disease Control and Prevention

Study Design

Allocation
RANDOMIZED
Purpose
ECT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
15 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-10-31
Completion
2005-03-31

Countries

  • Malawi

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00126906 on ClinicalTrials.gov