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Magnetic Resonance Imaging (MRI) for Aortic Dissection to Visualise Inflammation

NCT03948555 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2021-05-03

No results posted yet for this study

Summary

The study is a single-centre, prospective, observational cross-sectional imaging study aimed to determine if macrophage-mediated inflammation can be visualised in the aorta of patients with aortic dissection (AD) using ultrasmall super paramagnetic iron oxides (USPIO)-enhanced magnetic resonance imaging (MRI).

Conditions

  • Aortic Dissection
  • Aortic Diseases

Interventions

DIAGNOSTIC_TEST

Magnetic Resonance Imaging (MRI) using ultrasmall super paramagnetic iron oxides (USPIOs)

All patients will undergo two MRI scans (one MRI scan pre-USPIO administration, and one MRI scan 24-36 hours following USPIO administration) and blood samples will be taken for future biomarker analysis.

Sponsors & Collaborators

  • University of Leicester

    lead OTHER

Principal Investigators

  • Toru Suzuki, MD, PhD · University of Leicester

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-11
Primary Completion
2022-03-31
Completion
2022-03-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03948555 on ClinicalTrials.gov