MedTrace Logo

The Effect of Platelet Rich Plasma on Pain at Skin Graft Donor Sites

NCT03937765 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2024-03-22

No results posted yet for this study

Summary

The purpose of this study is to compare post-operative skin graft donor site pain between those treated with standard wound care vs PRP. Secondarily the study is designed to compare time to complete donor site healing. The null hypothesis is that here is no difference in post-operative donor site pain between those treated with standard wound care and PRP. The secondary null hypothesis is that there is no difference in time to donor site healing.

Conditions

  • Skin Graft (Allograft) Rejection
  • Skin Graft Complications
  • Skin Graft Detachment
  • PRP

Interventions

PROCEDURE

PRP harvest and preparation

The PRP harvest and preparation will be done in the operating room with the help of the hospital blood bank. The skin graft surgery will be completed by Dr. Jason Lowe and/or one of the Orthopaedic Surgery residents. Follow up will also be completed by Dr. Lowe or one of the residents. Data analysis will be done by Drs. Lowe and Manoharan. Each patient that will be undergoing a skin graft surgery will be randomized into either the PRP (intervention) group or the control group. Follow up and dressing changes will be the same for both groups. Each group will be prescribed a multi-modal pain regimen to reduce narcotic usage.

Sponsors & Collaborators

  • University of Arizona

    lead OTHER

Principal Investigators

  • Aditya Manoharan, MD · University of Arizona College of Medicine Department of Orthopaedic Surgery

  • Jason Lowe, MD · University of Arizona College of Medicine Department of Orthopaedic Surgery

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2024-03-15
Completion
2024-03-15

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03937765 on ClinicalTrials.gov