Influence of Platelet Concentrates on Wound Healing
NCT03667638 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2018-09-12
Summary
Chronic soft tissues defects can extend into the fat layer or even deeper and can cause functional disadvantages. Split-thickness skin grafts (STSGs) used to cover these wounds have varying success rates. To improve wound healing in chronic wounds the authors have studied the application of autologous platelet concentrates in a human keratinocyte culture model in vitro and in a combination with surgical procedures in vivo as second line therapy in patients with initially failed wound closure.
Conditions
- Platelet-Rich Plasma
- Wound Healing Delayed
Interventions
- COMBINATION_PRODUCT
-
Platelet-Rich Plasma
Adding PRP to wound bed during surgical debridement
Sponsors & Collaborators
-
Hannover Medical School
lead OTHER
Principal Investigators
-
Peter Vogt, MD · Medical School Hannover
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-11-30
- Primary Completion
- 2017-11-30
- Completion
- 2017-12-31
Countries
- Germany
Study Locations
More Related Trials
-
Cutaneous Microcirculation After Plasma Therapy
NCT02417818 ·Status: COMPLETED ·Phase: NA
-
Wound Additives in Primary Total Joint Athroplasty
NCT03158623 ·Status: COMPLETED ·Phase: PHASE3
-
Local Injection of PRP During Repair of Disrupted Surgical Wounds
NCT03781882 ·Status: COMPLETED ·Phase: NA
-
A Comparative Study of Platelet-Rich Plasma and Normal Saline Dressings in the Treatment of Chronic Wounds (PRP-NS Wound T)
NCT06849232 ·Status: COMPLETED ·Phase: NA
-
Application of Cultured Autologous Keratinocytes for Burn Wound Healing
NCT00832156 ·Status: COMPLETED ·Phase: PHASE3
-
Recipient Site Pre-conditioning in Fat Grafting
NCT03393598 ·Status: COMPLETED ·Phase: NA
-
Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring
NCT05311124 ·Status: UNKNOWN ·Phase: NA
-
Adipose Tissue Extract and Platelet-rich Plasma Use for Wound Healing
NCT02799290 ·Status: COMPLETED ·Phase: PHASE2
-
Obtaining and Storing Blood Samples and Debridement Samples for Wound Related Research
NCT00762697 ·Status: COMPLETED
-
Efficacy of Platelet Rich Plasma Injection Plus Fat Grafting as Compared to Fat Grafting Alone on Burn Scar by Using Vancouver Scar Scale
NCT04781348 ·Status: COMPLETED ·Phase: PHASE4
-
Use of Platelet-enriched Plasma During Auricular Reconstruction
NCT03215979 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Platelet Rich Plasma in Skin Graft Take for Patients With Post Burn Raw Areas
NCT05996614 ·Status: UNKNOWN ·Phase: NA
-
Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - A Study in "Split Wound Design"
NCT03668665 ·Status: WITHDRAWN ·Phase: PHASE3
-
Efficacy of Topical Heparin Spray on Donor Site Wound Healing Time Compared to Conventional Dressing Among Patients Undergoing Split Thickness Skin Grafting
NCT04613336 ·Status: UNKNOWN
-
Controlled Comparison of a Traditional Dressing Versus a Biologic Dressing Composed of Fetal Fibroblasts and Keratinocytes in Association With a Collagen Matrix on Skin Donor Sites
NCT03334656 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds
NCT07318792 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Cutaneous Microcirculation After Remote Ischemic Preconditioning
NCT02417805 ·Status: COMPLETED ·Phase: NA
-
Free Skin Grafting to Reconstruct Donor Sites After Radial Forearm Flap Harvesting
NCT05137639 ·Status: COMPLETED ·Phase: NA
-
A Retrospective Analysis of Patients With Full Thickness Wounds on a Case by Case Basis
NCT00764088 ·Status: COMPLETED
-
Dermal Micrografts in Regenerative Surgery
NCT03912675 ·Status: COMPLETED ·Phase: NA
-
Effect of Collagenase on Healing and Scarring
NCT00651820 ·Status: COMPLETED ·Phase: PHASE4
-
Platelet Rich Plasma (PRP) as a Treatment for ACHILLES Tendon Tears
NCT00731068 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars
NCT03935594 ·Status: TERMINATED ·Phase: PHASE2
-
Fat Grafts With Adipose-derived Regenerative Cells for Soft Tissue Reconstruction in Children
NCT03806361 ·Status: COMPLETED ·Phase: NA
-
Cutaneous Remote Ischemic Preconditioning in Plastic Surgery
NCT01235286 ·Status: COMPLETED ·Phase: NA