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Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease

NCT03921242 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 4888

Last updated 2023-11-09

No results posted yet for this study

Summary

This is a proposal for a retrospective observational study of the safety of metformin use in patients with chronic kidney disease, compared to other commonly used diabetes drugs. It will be conducted using retrospective data from the New York City CDRN, Medicare administrate files, and New York State Medicaid administrative files, which will be linked and then deidentified prior to analysis.

Conditions

  • Diabetes Mellitus, Type 2
  • Renal Insufficiency, Chronic

Interventions

DRUG

Metformin

Newly Initiated and regular metformin dosage as prescribed by each patient's medical care provider

DRUG

Sulfonylurea

Newly initiated and regular sulfonylurea dosage as prescribed by each patient's medical care provider

DRUG

DPP-4 inhibitor

Newly initiated and regular DPP-4 inhibitor dosage as prescribed by each patient's medical care provider

DRUG

SGLT2 inhibitor

Newly initiated and regular SGLT2 inhibitor dosage as prescribed by each patient's medical care provider

DRUG

GLP1 receptor agonist

Newly initiated and regular GLP1 receptor agonist dosage as prescribed by each patient's medical care provider

Sponsors & Collaborators

  • Patient-Centered Outcomes Research Institute

    collaborator OTHER

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Alvin Mushlin · Weill Cornell Medical College/Memorial Sloan Kettering Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-08-01
Primary Completion
2023-08-01
Completion
2023-08-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03921242 on ClinicalTrials.gov