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Spatial Analysis of the Intestinal Microbiota in Healthy Subjects

NCT03918330 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2025-03-27

No results posted yet for this study

Summary

Research on the human intestinal microbiota is common as there is rising evidence of its influence on host physiology and several diseases. Predominantly, it has been based on analyses of faecal samples because of their easy sampling. A minority of studies investigated the gut microbiota using mucosal samples. Not much is known about the spatial differences in microbiota composition along the large bowel. The spatial differences of the gut microbiota without preparation of the bowel have not been analysed yet. Furthermore, the composition of the microbiota of the luminal gut content has not been analysed yet.

This study aims to gain knowledge of the microbial composition of luminal and mucosal samples at different segments of the lower gastrointestinal tract: ileum, caecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum, as well as of rectal swabs and faecal samples.

Conditions

  • Healthy Subjects

Sponsors & Collaborators

  • Region Örebro County

    collaborator OTHER

  • Örebro University, Sweden

    lead OTHER

Principal Investigators

  • Robert Brummer, Prof. · Region Örebro County, Örebro University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-08-01
Primary Completion
2019-02-28
Completion
2024-10-10

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03918330 on ClinicalTrials.gov