Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation
NCT03906331 · Status: APPROVED_FOR_MARKETING · Type: EXPANDED_ACCESS
Last updated 2025-01-17
Summary
Expanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other considerations that prevent access to selpercatinib through an existing clinical trial.
The treating physician/investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.
Conditions
- Non Small Cell Lung Cancer
- Medullary Thyroid Cancer
- Colon Cancer
- Breast Cancer
- Pancreatic Cancer
- Papillary Thyroid Cancer
- Other Solid Tumors With Evidence of Activating RET Alteration
Interventions
- DRUG
-
Open-label expanded access
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Contact Lilly at 1-800-LillyRx (1-800-545-5979) · Eli Lilly and Company
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
- Australia
- France
- Germany
- Hong Kong
- Israel
- Italy
- Japan
- New Zealand
- Poland
- Singapore
- Spain
- Switzerland
Study Locations
More Related Trials
-
Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast Cancer
NCT00739063 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Prexasertib (LY2606368) in Participants With Advanced Cancer
NCT02778126 ·Status: COMPLETED ·Phase: PHASE1
-
Expanded Access to Veliparib
NCT03123211 ·Status: NO_LONGER_AVAILABLE
-
A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants
NCT06215521 ·Status: COMPLETED ·Phase: PHASE1
-
Retroprospective Real Life Observatory of Eribulin
NCT02393287 ·Status: COMPLETED
-
A Study of LY3023414 in Participants With Advanced Cancer
NCT01655225 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Pirtobrutinib (LOXO-305) in Healthy Adult Participants
NCT06181006 ·Status: COMPLETED ·Phase: PHASE1
-
Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer
NCT02929862 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
NCT07306559 ·Status: RECRUITING ·Phase: PHASE1
-
LY3023414 and Prexasertib in Metastatic Triple-negative Breast Cancer
NCT04032080 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study of Single Agent Lenvatinib
NCT03168074 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
NCT07213791 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Two Different Formulations of Pirtobrutinib (LOXO-305) In Healthy Participants
NCT06258174 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Trial Testing Oral Administration of Lucitanib in Patients With Fibroblast Growth Factor Receptor (FGFR)1-amplified or Non-amplified Estrogen Receptor Positive Metastatic Breast Cancer
NCT02053636 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment
NCT00190697 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of LY3007113 in Participants With Advanced Cancer
NCT01463631 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors
NCT03693014 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase III Trial of Pertuzumab Retreatment in Previously Pertuzumab Treated Her2-Positive Advanced Breast Cancer
NCT02514681 ·Status: COMPLETED ·Phase: PHASE3
-
Erlotinib in Combination With Pralatrexate in Advanced Malignancies
NCT01532011 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma
NCT06066333 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
NCT03125902 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In
NCT02708680 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
High Throughput Technologies to Drive Breast Cancer Patients to Specific Phase I/II Trials of Targeted Agents
NCT01414933 ·Status: COMPLETED
-
Utilizing Multiomic Advanced Diagnostics to Identify CDK 4/6 Inhibitor Response Predictors and a Post-treatment Multiomic Signature for Patients With ER+/HER2- Metastatic Breast Cancer
NCT03195192 ·Status: COMPLETED ·Phase: NA
-
"neoBREASTIM": Atezolizumab Plus RP1 Oncolytic Immunotherapy in the NeoAdjuvant Setting of Triple-Negative Breast Cancer
NCT06067061 ·Status: TERMINATED ·Phase: PHASE1/PHASE2