Erector Spinae Plane Block Versus Intercostal for VATS

Summary

The Erector Spinae Plane (ESP) block is a new interfascial regional anesthesia technique recently described by Forero et al. Currently the literature shows the ESP block being used for analgesia after thoracic surgery, breast surgery, abdominal surgery (visceral abdominal analgesia in bariatric surgery, ventral hernia repair, cholecystectomy), thoracic vertebral surgery and for pain relief in rib fractures. Taking in consideration the excellent clinical experience, but the lack of strong and high-quality evidence, supporting the use of ESP block for pain management in patients undergoing VATS procedures, there is a specific interest to develop a prospective study. Comparing the effect of the current pain relief strategy at the MGH (intercostal nerve block by the surgeon at the end of the procedure ) versus ESP block after VATS, seems warranted to improve current clinical results.

Conditions

• Lung Cancer
• Lung Diseases

Interventions

PROCEDURE

ESP block

ESP with 20 ml of Bupivacaine 0.25%, Epinephrine 5mcg/ml and Dexamethasone 10mg. Sham intercostal block with 20 ml Normal Saline

PROCEDURE

Intercostal block

Intercostal block with 20 ml of Bupivacaine 0.25%, Epinephrine 5mcg/ml and Dexamethasone 10mg. Sham ESP with 20 ml Normal Saline

PROCEDURE

Sham ESP block

As described earlier

PROCEDURE

Sham Intercostal block

As described earlier

DRUG

Bupivacaine-epinephrine

As described earlier

DRUG

Dexamethasone injection

As described earlier

DRUG

Normal saline

As described earlier

Sponsors & Collaborators

• McGill University Health Centre/Research Institute of the McGill University Health Centre

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-06-26

Primary Completion

2021-06-20

Completion

2021-06-20

Countries

• Canada

Study Locations