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Development of Novel Measures for Alzheimer's Disease Prevention Trials

NCT03900273 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2025-10-31

No results posted yet for this study

Summary

This protocol focuses on novel measures of cognition and everyday function that have robust psychometrics and reduced practiced effects. They will be deployed in a parallel group study in which participants are randomized to assessment type (novel vs established) and receive serial assessments over a one year period in order to highlight contrasts between novel and established measures.

Conditions

  • Healthy Participants

Interventions

OTHER

No Practice Effects (NPE) cognitive battery, and Miami Computerized Functional Assessment Scale (CFAS)

Novel measures of Cognitive and Everyday function

OTHER

Preclinical Alzheimer's Cognitive Composite (PACC), Alzheimer's Disease Assessment Scale-Cognitive Scale (ADAS-Cog), and Functional Assessment Questionnaire (FAQ)

Established measures of Cognitive and Everyday Function

Sponsors & Collaborators

  • Columbia University

    collaborator OTHER

  • University of Southern California

    collaborator OTHER

  • Feinstein Institute for Medical Research

    collaborator OTHER

  • University of Miami

    collaborator OTHER

  • New York State Psychiatric Institute

    lead OTHER

Principal Investigators

  • Terry E. Goldberg, Ph.D. · Columbia University Medical Center/ New York State Psychiatric Institute

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-25
Primary Completion
2025-08-31
Completion
2026-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03900273 on ClinicalTrials.gov