Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease
NCT00257673 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 183
Last updated 2008-05-06
Summary
The purpose of this study is to determine in a 12-week treatment study if MEM 1003 is a safe and effective treatment for patients with mild to moderate Alzheimer's disease.
Conditions
Interventions
- DRUG
-
MEM 1003
30 mg twice a day
- DRUG
-
MEM 1003
90 mg MEM 1003 twice a day
- DRUG
-
Placebo for MEM 1003
Placebo twice a day
Sponsors & Collaborators
-
Memory Pharmaceuticals
lead INDUSTRY
Principal Investigators
-
Stephen Murray, MD, PhD · Memory Pharmaceutical Corp.
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-11-30
- Primary Completion
- 2007-10-31
- Completion
- 2007-10-31
Countries
- United States
Study Locations
More Related Trials
-
Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease
NCT00933608 ·Status: COMPLETED ·Phase: PHASE4
-
The Use of Memantine for Prevention of Alzheimer's Disease
NCT05063851 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease
NCT00930059 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO5313534 as Add-on to Donepezil Treatment in Patients With Mild to Moderate Alzheimer's Disease
NCT00884507 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
NCT00105547 ·Status: COMPLETED ·Phase: PHASE3
-
Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: Health Outcome
NCT02854917 ·Status: COMPLETED
-
Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease
NCT00857233 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease
NCT00663936 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease
NCT03625622 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease (US202)
NCT02079909 ·Status: COMPLETED ·Phase: PHASE2
-
Preliminary Efficacy and Safety Study of ST101 in Alzheimer's Disease
NCT00842673 ·Status: COMPLETED ·Phase: PHASE2
-
A Multiple Dose Study of PF-04360365 In Patients With Mild to Moderate Alzheimer's Disease
NCT00945672 ·Status: COMPLETED ·Phase: PHASE2
-
Study of LM11A-31-BHS in Mild-moderate AD Patients
NCT03069014 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients
NCT00255086 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease
NCT03289143 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
NCT00838110 ·Status: COMPLETED ·Phase: PHASE3
-
Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease
NCT05267535 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease
NCT03867253 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease
NCT01397578 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of AD-35 in Treatment of Subjects With Mild to Moderate Alzheimer's Disease
NCT03625401 ·Status: UNKNOWN ·Phase: PHASE2
-
Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
NCT00545974 ·Status: COMPLETED ·Phase: PHASE4
-
Safety Study of HPP854 in Subjects With Mild Cognitive Impairment or a Diagnosis of Mild Alzheimer's Disease
NCT01482013 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION)
NCT02615002 ·Status: COMPLETED ·Phase: PHASE2
-
The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease
NCT01921972 ·Status: COMPLETED ·Phase: PHASE4
-
SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00093951 ·Status: COMPLETED ·Phase: PHASE2