Evaluation of the Effect of Different Cleaning and Disinfection Procedures on the Involvement of Candida Species

NCT03894839 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2019-03-29

No results posted yet for this study

Summary

Individuals may experience tooth loss as a result of trauma, periodontal destruction, lack of adequate bone support and clinically dental mobility. The increase in these tooth loss results in a condition called complete toothlessness in patients, and as a result of this, dentists treat complete dentures. It is known that the microorganism retention in the existing restorations is faster and higher than the natural tissues, and this leads to faster plaque build-up and hence bad odor. Candida species are common in oral flora, because they are numerous in the mouth and they are opportunistic pathogenic fungi that can make superficial and deep infections. The most important pathogen species among these parasites is Candida albicans. Mouth moniliasis or acute pseudomembrane candidiasis in the oral cavity of the so-called canker is caused by C.albicans. Chronic hyperplastic candidiasis is a clinical entity that is clinically inseparable from leukoplakia and completely separate from thrush. The accumulation of microorganisms in prosthetic materials is very important for the protection of the health of oral tissues and it is desirable to use appropriate cleaning and disinfection materials to minimize this accumulation.

It is known in the literature that ozone and microwave technologies are used as disinfection technique. In this study, the application of ozone and microwave technologies in addition to the cleaning agents used as standard treatment will be compared in vivo. No such research has been found.The aim of this study was to evaluate the effect of different cleaning and disinfection procedures on the involvement of Candida species in complete denture patients.

Conditions

  • Candidiasis, Oral

Interventions

OTHER

glutaraldehyde disinfection and microwave application

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

OTHER

Chlorhexidine gluconate disinfection and microwave application

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

OTHER

Sodium hypochlorite disinfection and microwave application

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

OTHER

glutaraldehyde disinfection and ozone therapy

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

OTHER

Chlorhexidine gluconate disinfection and ozone therapy

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

OTHER

Sodium hypochlorite disinfection and ozone therapy

Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists

Sponsors & Collaborators

  • Yuzuncu Yıl University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-26
Primary Completion
2018-10-26
Completion
2019-01-22

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03894839 on ClinicalTrials.gov