Evaluation of the Effect of Different Cleaning and Disinfection Procedures on the Involvement of Candida Species
NCT03894839 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2019-03-29
Summary
Individuals may experience tooth loss as a result of trauma, periodontal destruction, lack of adequate bone support and clinically dental mobility. The increase in these tooth loss results in a condition called complete toothlessness in patients, and as a result of this, dentists treat complete dentures. It is known that the microorganism retention in the existing restorations is faster and higher than the natural tissues, and this leads to faster plaque build-up and hence bad odor. Candida species are common in oral flora, because they are numerous in the mouth and they are opportunistic pathogenic fungi that can make superficial and deep infections. The most important pathogen species among these parasites is Candida albicans. Mouth moniliasis or acute pseudomembrane candidiasis in the oral cavity of the so-called canker is caused by C.albicans. Chronic hyperplastic candidiasis is a clinical entity that is clinically inseparable from leukoplakia and completely separate from thrush. The accumulation of microorganisms in prosthetic materials is very important for the protection of the health of oral tissues and it is desirable to use appropriate cleaning and disinfection materials to minimize this accumulation.
It is known in the literature that ozone and microwave technologies are used as disinfection technique. In this study, the application of ozone and microwave technologies in addition to the cleaning agents used as standard treatment will be compared in vivo. No such research has been found.The aim of this study was to evaluate the effect of different cleaning and disinfection procedures on the involvement of Candida species in complete denture patients.
Conditions
- Candidiasis, Oral
Interventions
- OTHER
-
glutaraldehyde disinfection and microwave application
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
- OTHER
-
Chlorhexidine gluconate disinfection and microwave application
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
- OTHER
-
Sodium hypochlorite disinfection and microwave application
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
- OTHER
-
glutaraldehyde disinfection and ozone therapy
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
- OTHER
-
Chlorhexidine gluconate disinfection and ozone therapy
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
- OTHER
-
Sodium hypochlorite disinfection and ozone therapy
Combination of the chemical disinfection which could be done by patients and professional disinfection methods which is done by dentists
Sponsors & Collaborators
-
Yuzuncu Yıl University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-10-26
- Primary Completion
- 2018-10-26
- Completion
- 2019-01-22
Countries
- Turkey (Türkiye)
Study Locations
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